The Effects Of Treadmill Running On Alzheimer Disease

Little information is known about the use of treadmill running to attenuate or reverse the cognitive decline due to Alzheimer Disease. The study reviewed in this paper by Jinkyung et. al set out to determine if exercise can prevent cognitive decline in the early and late stages of Alzheimer Disease. Benefits to using exercise as a non-pharmacological method of offsetting the effects of this disease include little to no side effects for the patient; low cost to patient and health care system; exercise may have a preventative factor to Alzheimer Disease, unlike pharmacological treatments. Previous studies have reviewed voluntary wheel running in triple transgenic mice (3xTG-AD), the current study is the first to examine the effects of treadmill running in the 3xTG-AD mice. 3xTG-AD Mice have genes that act similarly to human Alzheimer Disease progression, thus they make an appropriate non-human animal to study from. 3xTG mice at 24 months of age were divided into 2 categories. 8 mice with Alzheimer Disease did not exercise and were one of the control groups. 8 mice with Alzheimer Disease exercised and served as the intervention group. An additional 8 mice served as another control group but differed in that they were a wild type mice. At 4 and 24 months of age the intervention group of mice were forced to follow a treadmill protocol for 30 mins 5d/wk for 12 wks. The exercise sessions included 5 minutes of warm up at 5 meters per minute followed by a 20 minute exercise sessionShow MoreRelatedEssay on Who Needs Sleep?1546 Words   |  7 Pagescomparison to healthy controls those with BPD have more stage 1 sleep and less stage 4 sleep† (Selby). People know they need sleep, but the effects of lack of sleep are just as great. Sleep is the natural way to keep up on mental and physical wellness and it is underused. Although people may recognize the need for sleep, they do not know the harmful effects of sleep deprivation; such as, decreasing performance, a shorter life span, and borderline personality disorders. Today everything is made a